In vitro asseement of the anti bacterial activity of ethanolic aeriel part extract of momordica foetida extract on the armpit flora
Abstract
ABSTRACT.
Momordica foetida is a perennial herb with creamy flowers with reddish or orange center and having both female and male flowers on same plant. The fruit is bright orange with prickles on a
beautiful plant but very unpleasant smell that belong to Cucurbitaceae family.
The aerial parts of Momordica foetida was used, crushed and its contents extracted using,
9 8 % ethanol (alcohol). The antibacterial activity of the extract was tested on the axilla swab and. susceptible staphylococcus aureus A TCC 25953. The axilla swab from two patients who had experienced the bad odor were then cultured on the blood agar for 24hours at a temperature of
37.7°C. the grown microorganisms were exposed to the ethanolic extract of Momordica foetida and later also incubated at above stated conditions for the same period.
The biggest zone of inhibition was seen with 200mg/ml concentration but the MIC was seen with
25mg/ml concentration of the ethanolic aerial extract of Momordica foetida. That was for both axilla swabs and also for staphylococcus aureus ATCC 25953.The graph pad prism 7 was run to compare the zones of inhibition between the negative control and the extract and p-value of
0.0001 was obtained indicating a high level of significance.
There is significant antibacterial activity of the ethanolic aerial extract of Momorclica foeti cia on the staphylococcus aureus as shown by the p-value.Sorne bacteria in the armpit swab were susceptible and others were not susceptibale