The banking sector is experiencing profound technological advancements,from mobile and electronic banking via apps to Artificial Intelligence today. The adoption of Artificial Intelligence to perform banking activities has inevitably impacted how banks operate and serve their customers thus greatly impacting the bank-customer relationship. However,certain risks are associated with Artificial Intelligence in banking, which necessitates regulatory frameworks to mitigate the risks while encouraging innovation. This dissertation sets out to analyze the Impacts of Artificial Intelligence on the Bank-Customer relationship and the regulatory efforts being taken to regulate Artificial Intelligence in banking to protect customers against associated risks. In going about this task, I examine the way Artificial Intelligence has redefined bank-customer relationship and drawing inspiration form different jurisdictions, in particular, United States, China and Europe analyze the efficacy of the regulatory efforts being taken.