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Prevalence of extended spectrum beta lactamase resistance genes (CTX-M and TEM) among Escherichia coli isolates from Entebbe Regional Referral Hospital
(Makerere University, 2022-02)
Introduction
ESBL producing bacteria prevalence is on the rise and ESBL producing E.coli have been implicated in many urinary tract infections as well as septicemia. Such infections may result in prolonged hospital stays, ...
Carriage of NDM and IPM carbapenem resistance genes among E.coli and K.pneumoniae isolates from Mbarara
(Makerere University, 2022-03)
Background: The increasing prevalence of carbapenem-resistant Enterobacteriaceae strains is related to high mortality and it is increasing around the world. Among the Enterobacteriaceae family, Klebsiella pneumoniae and ...
Prevalence of quinolone resistant gene qep in uropathogenic escherechia coli isolates from female patient samples at the Microbiology Laboratory Makerere University College of Health Sciences
(Makerere Univeristy, 2022-01)
Background
Drug resistant Escherichia coli (E Coli) is the leading cause of community and hospital acquired urinary tract infections affecting approximate 150 million people each year worldwide. Uropathogenic Escherichia ...
Prevalence of the TEM gene in Eschericia coli and Klebseilla pneumoniae isolates from clinical microbiology laboratory
(Makerere University, 2022-12-20)
Background
Antimicrobial resistance poses a significant obstacle to the effective treatment of diseases everywhere. In enterobacteriaceae, the TEM gene is a crucial contributor to resistance. There is a significant vacuum ...
Development of a herbal oral suspension from combined ethanolic extracts of Tamarindus indica and Phyllanthus niruri against uropathogenic Escherichia coli
(Makerere University, 2022-09)
Introduction
Urinary tract infections (UTIs) are among the most frequent causes of morbidity (Moyo et al., 2010). Global disease burden study of 2019 reported a 48.57% increase in UTIs incidence rate compared to 1990. ...
Prevalence of NDM and OXA 48 genes in E.coli and K. pneumoniae isolates from Mulago National Referral Hospital
(Makerere University, 2022-03)
Carbapenems are the drugs of choice for severe ESBL producing Gram negative bacteria. In recent findings Gram negative bacteria in particular E. coli and K. pneumoniae have evolved new genes that is NDM and OXA-48. These ...
Prevalence of SHV gene in Escherichia coli and Klebsiella pneumoniae isolates from Microbiology Laboratory
(Makerere University, 2022-12-06)
Introduction: Antibiotic resistance due to beta lactamases is one of the most forms seen in many bacteria. Other forms of bacterial resistance include; limiting uptake of drugs modifying drug target, efflux of drugs through ...
Prevalence of Tem Gene among Escherichia coli and Klebsiella pneumoniae isolates from the Microbiology Laboratory
(Makerere University, 2022-12)
Introduction
Presently, antimicrobial resistance to various drug classes has been noted as a major global health threat. Extended Spectrum Beta Lactamases (ESBLs) are derived from genes for the narrow-spectrum beta-lactamases ...
Prevalence of the TEM gene among Eschericia coli and Klebseilla pneumoniae isolates from microbiology laboratory
(Makerere University, 2022-12-13)
Background: Extended spectrum beta lactamases play a key role in antimicrobial resistance by inhibiting the beta lactams such as the cephalosporins and penicillins preventing the drugs from killing the Enterobacteriaceae. ...
Prevalence of SHV gene amongst archived Enterobacteriacaea DNA isolates in the Molecular Laboratory of Makerere University
(Makerere University, 2022)
Background: Multidrug resistance is a great problem in the treatment of infections especially from the gram-negative bacilli. The gram-negative bacilli have a wide range of mechanism used in the resistance including the ...