Browsing School of Biosciences Collection by Title "Characterisation of paraoxonase-1 gene polymorphism as a biomarker of oxidative stress in sickle cell disease patients in Uganda"
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Characterisation of paraoxonase-1 gene polymorphism as a biomarker of oxidative stress in sickle cell disease patients in Uganda
(Makerere University, 2022-09)Oxidative stress, chronic inflammation, vasoocclusion, and free iron are all features present in sickle cell disease. Paraoxonases are a family of antioxidant enzymes with anti-inflammatory and anti-oxidative action. However ...