Prevalence of Extended-Spectrum Beta-lactamase resistant genes (CTX-M and TEM) among Escherichia coli isolates from Entebbe.

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dc.contributor.author Achola, Jemimah Faith
dc.date.accessioned 2023-03-17T08:58:37Z
dc.date.available 2023-03-17T08:58:37Z
dc.date.issued 2022-02
dc.description A dissertation submitted to Makerere University School of Biomedical Sciences in partial fulfillment of the requirements for the award of the Bachelors Degree of Sciences iIn Biomedical Sciences. en_US
dc.description.abstract This study investigates the prevalence of ESBL genes (CTXM and TEM) among E.coli isolates obtained from Entebbe Regional Referral Hospital. 32 E.coli isolates were collected from patients not responding to treatment at the hospital. Molecular detection of antibiotic resistance genes was done on all 32 isolates. Out of the 32 isolates, 7 were found to carry the TEM gene, and the prevalence of the gene was 21%. 1 out of 32 isolates (3%) was found to carry the CTXM gene. The results revealed that TEM was the most frequent ESBL type (21%), followed by CTXM (3%) isolates. There was no occurrence of more than one gene in all of the isolates. The results indicate that there is a presence of ESBL genes associated with antimicrobial resistance among the E.coli isolates from Entebbe regional referral hospital. There is a need for surveillance measures to be taken to control the spread among the community. en_US
dc.description.sponsorship Makerere University College of Health Sciences, Mulago. en_US
dc.identifier.citation Achola, J. F. (2022) Prevalence of Extended-Spectrum Beta-lactamase resistant genes (CTX-M and TEM) among Escherichia coli isolates from Entebbe (Unpublished undergraduate dissertation). Makerere University, Kampala, Uganda.ished undergraduate dissertation). Makerere University, Kampala, Uganda. en_US
dc.identifier.uri http://hdl.handle.net/20.500.12281/15831
dc.language.iso en en_US
dc.publisher Makerere University en_US
dc.subject Extended Spectrum Beta-Lactamase Resistant Genes (Ctxm and Tem) en_US
dc.subject Escherichia Coli Isolates en_US
dc.subject Entebbe en_US
dc.title Prevalence of Extended-Spectrum Beta-lactamase resistant genes (CTX-M and TEM) among Escherichia coli isolates from Entebbe. en_US
dc.type Thesis en_US
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