dc.contributor.author | Ishaka, Ahmad | |
dc.contributor.author | Mulindwa, Joseph Stuarts | |
dc.contributor.author | Katushabe, Lydia | |
dc.date.accessioned | 2022-05-10T14:12:45Z | |
dc.date.available | 2022-05-10T14:12:45Z | |
dc.date.issued | 2021-12 | |
dc.identifier.citation | Ishaka, A, (2021). Development of an anti-acne cream containing a combination of extracts of aloe barbadensis gel and eucalyptus globulus oil (Unpublished undergraduate dissertation). Makerere University, Kampala, Uganda. | en_US |
dc.identifier.uri | http://hdl.handle.net/20.500.12281/12322 | |
dc.description | A research report submitted to the department of Pharmacy in partial fulfillment of the requirement for the award of the degree of bachelor of Pharmacy at Makerere University. | en_US |
dc.description.abstract | Introduction; Acne vulgaris is a pilosebaceous unit skin disease that affects the face, back, and
trunk, which have the most oil glands with the most prevalent signs being seborrhea, comedones,
and inflammatory lesions. The standard treatments for acne vulgaris are topical and systemic
retinoids as well as antimicrobial agents whose excessive use has led to an increased resistance
from acne vulgaris causing bacteria which has necessitated interventions such as increased study
of antimicrobial activity of herbal preparations like Aloe barbadensis and Eucalyptus globulus.
Objectives; To validate the antibacterial activity of extracts of Aloe barbadensis leaf gel and
Eucalyptus globulus leaf oil and develop a topical cream of a combination of the extracts
effective against Propionibacterium acnes
Methods; The study was an experimental in vivo and in vitro and involved determination of the
antibacterial activity of individual and then combined extracts of Eucalyptus globulus and Aloe
barbadensis on Propionibacterium acnes. Animal models were used to assess the acute dermal
toxicity of the herbal formulation cream of extracts of Eucalyptus globulus and Aloe
barbadensis. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Makerere University | en_US |
dc.subject | Acne vulgaris | en_US |
dc.subject | seborrhea | en_US |
dc.subject | pilosebaceous unit | en_US |
dc.subject | comedone | en_US |
dc.subject | comedolytic | en_US |
dc.subject | Cream formulation | en_US |
dc.subject | propionibacterium acnes | en_US |
dc.subject | Eucalyptus Globulus | en_US |
dc.subject | Aloe Barbadensis | en_US |
dc.title | Development of an anti-acne cream containing a combination of extracts of aloe barbadensis gel and eucalyptus globulus oil. | en_US |
dc.type | Thesis | en_US |