| dc.description.abstract | Enterobacteriaceaeare a large family of gram-negative bacteria that are responsible for causing many Nosocomial infections and less commonly community-acquired infections, including urinary tract infections. This study was done to determine the resistance pattern of enterobacteriacea to beta lactam drugs among patients seeking treatment at Lubaga Hospital Out Patient Department.A cross-sectional study was conducted at Lubaga Hospital where by midstream Urine samples of 50 pregnant women were collected and inoculated into Cysteine Lactose Electrolyte Deficient medium (CLED). Colonies from CLED were sub cultured onto MacConkey agar and blood agar plates. Identification was done using cultural characteristics and a series of biochemical tests. A standard method of Agar disc diffusion susceptiblity testing method was used to determine drug susceptibility patterns of the isolates. Urine samples of 50 pregnant women collected, 43 patients were infected with Enterobacteriaceae bacteria giving an overall prevalence of 86%. The identified Enterobacteriaceaewere S. aureus (32%), E. Coli (20%), K. pneumoniae (18%) andP. vulgaris (16%). The identified bacteria were 100% susceptible to a carbapenen drug called Meropenem and were 100% resistant to a cephalosporin drug called Ceftazidime. In this study, E. Coli had the highest resistance (55.6%) to beta-lactam drugs, K. pneumoniae (40%), S. aureus (40%) and P. vulgaris (20%).This research demonstrated significant Enterobacteriaceae infections and multi drug resistance hence basing on these findings, clinicians should recommend drug susceptibility tests in improving prescription of beta lactam drugs for the treatment of infections due to Enterobacteriaceaebacteria. | en_US |
