School of Bio-Medical Sciences (Bio-Medical) Collection
Recent Submissions
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Development of a hand-made DNA extraction kit for bacterial samples in the genomic and molecular laboratory - Makerere University College of Health Sciences
(Mekerere University, 2023-05)DNA extraction is a critical step in molecular biology research, enabling the analysis of genetic material from various organisms. The development of efficient and reliable DNA extraction methods is essential for accurate ... -
Prevalence of CTXM-resistant gene among enterobacteriaceae isolates from Clinical Microbiology Laboratory at the College of Health Sciences Makerere University
(Makerere University, 2022)Background: Antimicrobial resistance refers to the inability to effectively prevent and cure a growing number of illnesses caused by microorganisms. It has become an alarming global issue. CTX-M genes are a complex family ... -
Prevalence of extended spectrum beta lactamase (ctxm and tem) drug resistant genes among eschelishia coli isolates from Entebbe Uganda.
(Makerere University, 2022-02-15)Introduction Existence of drug resistant genes is major constraint in the treatment and management of patients infected with E. coli and has facilitated the continued spread of diseases in the communities and increased ... -
Pattern of cervical cancer among females presenting to Makerere University Pathology Core Reference Laboratory. A 5-year review.
(Makerere University, 2022-09-30)The common cause of cervical cancer is Human Papilloma Virus (HPV). HPV is responsible for 99.7% of cervical cancer and Infects 75 - 80% of sexually active adults at some point, however, it can be cleared by the body’s ... -
Carriage of ndm & imp carbapenem resistance genes among e. Coli & k. Pneumoniae in human stool isolates from Mbarara hospital
(Makerere University, 2022-03)Escherichia coli and Klebsiella pneumoniae have become intrinsically resistant to many types of β-lactamase due to the emergence of organisms carrying NDM and IMP genes(Liang et al., 2020). Carbapenems, among the beta-lactams, ... -
Co–resistance between Flouroquinolones, Trimethoprim/Sulfamethoxazole (SXT), and aminoglycosides with extended spectrum B–lactameses (ESBLS) in Eschericia coli isolated from blood, pus and urine specimens at Makerere University Clinical Microbiology Laboratory
(Makerere University, 2023)Background The global emergence and spread of extended-spectrum beta-lactamases (ESBLs) producing Enterobacteriaceae have been threatening the ability to treat an infection. Hence, this study aimed to determine co – ... -
Pattern of cervical cancer among females presenting to Makerere University Pathology Core Reference Laboratory. A 5-year review
(Makerere University, 2022)The common cause of cervical cancer is Human Papilloma Virus (HPV). HPV is responsible for 99.7% of cervical cancer and Infects 75 - 80% of sexually active adults at some point, however, it can be cleared by the body’s ... -
Project technical report on the designing and development of a low-cost vibrating foot massager to prevent food ulceration in stage 4 patients with type2 diabetes
(Makerere University, 2023-07)This report is divided into four comprehensive chapters and it encompasses the technical aspects of the activities performed by team Biotailors during the entire Design course. The design process started with identifying ... -
Prevalence of CTXM gene in isolates of enterobacteriaceae collected from the Microbiology Laboratory
(Makerere University, 2022)Multi drug resistance in Enterobacteriaceae is a common cause of hospital and community acquired infections. Enterobacteriaceae are gram negative bacteria like E. coli, Klebsiella Pneumoniae are pathogenic organisms causing ... -
Antibiotic activity of turmeric, castor oil, honey and apple cider vinegar extracts on MRSA on isolates from medical microbiology laboratory, Makerere University.
(2023-12-15)Background Herbal medicine is used by approximately 80% of the world’s population according to WHO. In Uganda, herbal remedies play a significant role in the health care system being the oldest yet continuously utilized ... -
Design and evaluation of a solar-aided autoclave to aid in the prevention of neonatal sepsis in Uganda
(Makerere University, 2023)In Uganda, approximately 81 babies die each day before reaching their first month. As of 2016, Uganda had a neonatal mortality rate of 21.4 deaths per 1000 live births and an under-five mortality rate of 53.0 deaths per ... -
Redesign and evaluation of a bili-wear device for treating neonatal jaundice in low and middle-income countries
(Makerere University, 2023)Neonatal jaundice may be classed as physiological or pathological and is principally caused by an increase in serum bilirubin during the neonatal period, which causes yellow discoloration of the skin, mucous membranes, and ... -
Redesign, testing and evaluation of a patient heave for manual handling of patients by health workers
(Makerere University, 2023)This technical report presents the redesign process of a Patient Heave prototype, aiming to improve its functionality, safety, and user experience. The current prototype was evaluated, and its strengths and weaknesses ... -
Development and evaluation of in-house SARS-COV-2 RNA extraction kit at Genomics Molecular Biology Laboratory, College of Health Sciences, Makerere University
(Makerere University, 2023)Objective: The purpose of this research was to develope in-house RNA extraction kit for SARCOV-2 using readily available reagents at Genomics Molecular biology Laboratory. Methodology: The study was an applied experimental ... -
Development and evaluation of an in-house RNA Extraction kit for severe acute respiratory syndrome Corona Virus 2(SARS-COV-2)
(Makerere University, 2023)Major objective of the study: To develop an in-house RNA extraction kit for extraction of high quality RNA. Specific objectives of the study: To determine the reagents required to develop the in-house RNA Extraction ... -
Design And Development Of The Derma-Vacillation Device To Delay The Progression Of The Occurrence Of Stage One Pressure Ulcers In Low- And Middle-Income Countries.
(Makerere University, 2023-06)Pressure ulcers are a significant cause of mortality, particularly in low- and middle-income countries (LMICs). This study presents the development of a derma-vacillation device aimed at preventing pressure ulcers in LMICs, ... -
Design, testing and redevelopment of a contact-free door system to reduce high hospital acquired infections among health workers from door surfaces.
(Makerere University, 2023-06-16)Hospital-acquired infections (HAIs) among health workers usually result in their morbidity and mortality. Handwashing and use of manual and automatic hand sanitizing have been the most common measures put in place to ... -
Alcohol and substance abuse among the youth in Kamwokya slum in central division, Kampala district.
(Makerere University, 2023-12-08)Background: Alcohol and substance abuse has continued to be a serious health problem among the youth in Kamwokya slum, Central Division, Kampala district and it has been affecting the community for a long time. However, ... -
Design and development of the Akili supportive-heating brace for relieving low back pain in adults in low-and-middle income countries
(Makerere University, 2023-12-10)Low back pain (LBP) has been the leading cause of lives living with disabilities since 1990 and remains a significant global public health concern. LBP is the pain in posterior aspect of the body from the lower margin to ... -
Design, testing and modification of a low-cost electronic stethoscope to aid in auscultation during pneumonia diagnosis in children under five.
(Makerere University, 2023-06)The diagnosis of pneumonia relies primarily on the presented clinical signs and symptoms. One of the parameters investigated during the diagnosis is the patient’s lung sound, during which a stethoscope is used. The mechanical ...