The Antimicrobial effect of callistemon citrinus extract against streptococcus mutans
MetadataShow full item record
One of the important virulence properties of Streptococcus mutans is their ability to form biofilms known as dental plaque on tooth surfaces and is a primary an etiological agent in dental caries. The aim of the current study was to evaluate the antimicrobial activity of Callistemon strinus extract on Streptococcus mutans using agar well diffusion method. Amoxyllin was used as a standard, while distilled water, 50% ethanol and 50% petroleum were used as negative controls. The results of this study indicate that the antibacterial activity of the Citrinus extracts on the agar plates varied in different solvents. The petroleum ether extract exhibited a significant antimicrobial activity of 40.6mm against Streptococcus mutans, compared to the ethanolic sextract that exhibited a moderate antimicrobial activity of 22.3mm.The plant Callistemon Citrinus is enriched with significant antimicrobials due to the presence of active constituents like phenolic compounds, tannins and thereby justifying their use in the indigenous system of medicine. Such medicinal plants can be of a great importance in modification of available antibiotics to combart antibiotic resistance. Therefore, more research mainly based on chemistry to identify, isolate and purify the phytochemicals in petroleum ether, ethanolic and water leaf extracts of Callistemon Citrinus such that the tests are carried out on pure compounds to identify the exact compounds responsible for different activities.