dc.contributor.author | Musisi, Julius | |
dc.date.accessioned | 2023-02-09T14:09:17Z | |
dc.date.available | 2023-02-09T14:09:17Z | |
dc.date.issued | 2022-03-20 | |
dc.identifier.citation | Musisi, J. (2022). Carriage of NDM & IMP Carbapenem resistance genes among E. coli & K. pneumoniae isolates from Mbarara hospital.(MakUD) (unpublished undergraduate dissertation). Makerere university, Kampala, Uganda. | en_US |
dc.identifier.uri | http://hdl.handle.net/20.500.12281/15633 | |
dc.description | A dissertation submitted to the School of Biomedical Sciences in partial fulfillment for the award of Bachelor of Science in Biomedical Science of Makerere University | en_US |
dc.description.abstract | Background: The increasing prevalence of carbapenem-resistant Enterobacteriaceae strains is related to high mortality and it is increasing around the world. Among the Enterobacteriaceae family, Klebsiella pneumoniae and Escherichia coli are among the most common agents of community- and hospital-acquired infections and have reportedly high incidence of carbapenem-resistance. Thus, the purposes of this work were to estimate the frequency of NDM and IMP carbapenem-resistant genes in K. pneumoniae and E. coli in isolates from Mbarara.
Methods: This was a laboratory-based study conducted between December and February 2022, using of isolates of E. coli and K. pneumonia from stool samples from Mbarara, Uganda. NDM and IMP genes were detected using molecular method (PCR) at Molecular Laboratory, Makerere University.
Results: We found that the prevalence Carbapenem-resistant E. coli was 15.6%, with NDM contributing 9.4%) and IMP contributing 6.3%.
Conclusion: The prevalence of NDM and IMP is high. This is a great public health concern. We should comply with measures for controlling infection. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Makerere University | en_US |
dc.subject | Carriage of NDM & IMP | en_US |
dc.subject | Carbapenem resistance genes | en_US |
dc.subject | E. coli & K. pneumoniae isolates | en_US |
dc.subject | Mbarara hospital | en_US |
dc.title | Carriage of NDM & IMP Carbapenem resistance genes among E. coli & K. pneumoniae isolates from Mbarara hospital. | en_US |
dc.type | Thesis | en_US |