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Prevalence of the TEM gene in Eschericia coli and Klebseilla pneumoniae isolates from clinical microbiology laboratory
(Makerere University, 2022-12-20)
Background
Antimicrobial resistance poses a significant obstacle to the effective treatment of diseases everywhere. In enterobacteriaceae, the TEM gene is a crucial contributor to resistance. There is a significant vacuum ...
Prevalence of SHV gene in Escherichia coli and Klebsiella pneumoniae isolates from Microbiology Laboratory
(Makerere University, 2022-12-06)
Introduction: Antibiotic resistance due to beta lactamases is one of the most forms seen in many bacteria. Other forms of bacterial resistance include; limiting uptake of drugs modifying drug target, efflux of drugs through ...
Development of a herbal oral suspension from combined ethanolic extracts of Tamarindus indica and Phyllanthus niruri against uropathogenic Escherichia coli
(Makerere University, 2022-09)
Introduction
Urinary tract infections (UTIs) are among the most frequent causes of morbidity (Moyo et al., 2010). Global disease burden study of 2019 reported a 48.57% increase in UTIs incidence rate compared to 1990. ...
Optimization of recombinant expression of the Mycobacteria tuberculosis rhomboid protease 1 using Escherichia coli overexpression plasmid
(Makerere University, 2022-10)
The mycobacteria Rhomboid proteases (1 & 2) have been identified as novel targets for drug targeting in mycobacteria giving a ray of hope for the realisation of new drug candidates for the management not only multidrug-resistant ...