School of Bio-Medical Sciences (Bio-Medical): Recent submissions
Now showing items 41-60 of 116
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prevalence of extended spectrum beta-lactamase (CTXM and tem) drug resistance genes among klebsiella pneumoniae and e. coli isolatesfrom Entebbe
(Makerere University, 2022-03-24)The prevalence of extended spectrum beta-lactamase (ESBL) genes specifically CTXM and TEM, among Escherichia coli and Klebsiella pneumoniae isolates from Entebbe regional referral Hospital,Uganda was investigated in this ... -
Prevalence of the TEM gene among Eschericia coli and Klebseilla pneumoniae isolates from microbiology laboratory
(Makerere University, 2022-12-13)Background: Extended spectrum beta lactamases play a key role in antimicrobial resistance by inhibiting the beta lactams such as the cephalosporins and penicillins preventing the drugs from killing the Enterobacteriaceae. ... -
Validation of the simplified carbapenem inactivation method for detection of carbapenemase producing gram negative rods at the Medical Microbiology Laboratory
(Makerere University, 2022-10)Purpose: The purpose of the study was to validate the simplified Carbapenem inactivation method by determining the sensitivity and the specificity, this test is more reliable and time consuming compared to the modified ... -
Infection prevention and control in Mulago National Referral Hospital after the third wave of Covid-19
(Makerere University, 2022-09)Background On the global scale out of every 100 patients in acute care hospitals seven patients in high income countries and 15 patients in law and middle-income countries will acquire at least one nosocomial infection ... -
A low-cost manually operated physiotherapy device for alleviation of limb weakness due to prolonged bedrest
(Makerere University, 2022-09)This report encompasses the technical aspects of the activities performed by team MEDI-MINDS up to design III. The contents here in are divided into three sections: Section I-Review of Design I, Section II- Revision of ... -
Prevalence of ESBLs among E.coli and K.pneumoniae isolates from Mulago National Referral Hospital
(Makerere University, 2022-05)Background; Enterobacteriaceae are common causes of health care associated and community acquired infections yet resistance to the commonly used antibiotics for the infections is increasing. Knowledge about the numbers ... -
Prevalence of SHV gene amongst archived Enterobacteriacaea DNA isolates in the Molecular Laboratory of Makerere University
(Makerere University, 2022)Background: Multidrug resistance is a great problem in the treatment of infections especially from the gram-negative bacilli. The gram-negative bacilli have a wide range of mechanism used in the resistance including the ... -
Optimizing medical waste management through design, implementation and assessment of a hand-held sort-it device incorporating magnetic separation technology
(Makerere University, 2022-11)This report follows the activities of team Transcend Technologies in an effort to fulfil the requirements of the design course series for the period of 18th march 2021 to 24th September, 2022. This report discusses ... -
Prevalence of NDM and OXA 48 genes in E.coli and K. pneumoniae isolates from Mulago National Referral Hospital
(Makerere University, 2022-03)Carbapenems are the drugs of choice for severe ESBL producing Gram negative bacteria. In recent findings Gram negative bacteria in particular E. coli and K. pneumoniae have evolved new genes that is NDM and OXA-48. These ... -
Prevalence of Tem Gene among Escherichia coli and Klebsiella pneumoniae isolates from the Microbiology Laboratory
(Makerere University, 2022-12)Introduction Presently, antimicrobial resistance to various drug classes has been noted as a major global health threat. Extended Spectrum Beta Lactamases (ESBLs) are derived from genes for the narrow-spectrum beta-lactamases ... -
Infant warmer bag: a device designed to maintain the baby's normal body temperature during hypothermic conditions.
(Makerere University, 2022-09-23)Every year, over 20 million low birth weight and preterm babies are born in Uganda (Byaruhanga R, 2005) Of the 20 million births, 4 million babies die within their first 28 days of life majorly because of the inability ... -
A systematic approach to eye diagnosis in LMICs: Design of a funduscopy device for capturing eye images and make a corresponding diagnosis using eye images in a software database
(Makerere University, 2022-09-13)This is a technical report containing information on the activities carried out by team The Bekaz during the Biomedical Engineering Design IV course. This course is undertaken in Biomedical Engineering as a continuation ... -
A natural approach to circumvent shortages of distilled water in LMICS: a low-cost water purification unit
(Makerere University, 2022-09-23)In this document, some sections exhibit all the art, craft and techniques in the design activities for the Pharie team. These consist of the practical part of needs finding, needs screening and conceptualization of ... -
The prevalence of Escherichia Coli to third generation cephalosporins from Makerere University clinical microbiology laboratory specimen
(Makerere University, 2022-09-09)Introduction: The emergence of extended-spectrum beta-lactamase Enterobacteriaceae is of great concern: a phenomenon that worries clinicians and other healthcare workers due to the serious threat they pose to patients. ... -
Evaluation of the diagnostic yield of cell blocks in suspected malignant pleural effusions at Makerere University Core Pathology Laboratory
(Makerere University, 2022-09)Introduction: Tumors that arise from the mesothelium or metastasizing to the mesothelium cause malignant pleural effusion. The most frequent and critical diagnosis to be made or ruled out in undetected unilateral pleural ... -
Antibiotic activity of garlic, ginger and tamarind crude extracts on methicillin resistant staphylococcus aureus
(Makerere University, 2022-08)Introduction: Due to the increased resistance to antibiotics by bacteria like MRSA, antibiotics which were once used to treat these become less effective. As a result, medicinal plants could be a reliable alternative for ... -
Prevalance of ESBL and carbapenemase-producing klebsiella pneumoniae from clinical isolates at Makerere University Medical Microbiology Labaratory.
(Makerere University, 2022-10-04)Klebsiella pneumoniae is known normal flora of the gastrointestinal tract of humans. It belongs to the family Enterobacteriaceae and is associated with pneumonia in immunocompromised hosts. Other disease caused by ... -
Designing a low cost upper limb prosthesis for people living with upper limb disabilities in low and middle income countries using locally available materials
(Makerere University, 2020-12)The human hand is considered to be a very powerful tool for operating in any environment, and a very important means for physical and social interaction. It allows people to accomplish sophisticated movements, like abduction, ... -
Expression and purification of an in-house Phusion DNA Polymerase using Escherichia coli BL21 (DE3) cells
(Makerere University, 2022)Introduction: DNA polymerases are enzymes that play a major role in enabling scientists to replicate DNA from organisms for a variety of studies in Molecular Biology. For years these polymerases have been isolated from a ...