School of Bio-Medical Sciences (Bio-Medical): Recent submissions
Now showing items 81-100 of 116
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Prevalence of quinolone-resistant genes in uropathogenic Escherichia coli isolates for female patients’ samples at the microbiology and molecular biology laboratory Makerere University College of Health Sciences.
(Makerere University, 2022-02-24)Background Uropathogenic Escherichia coli causing urinary tract infections are a major public health issue menacing the effectual treatment of urinary tract infections among females. The use of quinolone antibiotics like ... -
In-house expression and purification of Phusion DNA polymerase for high fidelity polymerase chain reaction (PCR) amplification.
(Makerere University, 2022-04)Background: DNA polymerases are indispensable tools in the molecular biology field during synthesis of DNA molecules in the Polymerase Chain Reaction (PCR). Phusion DNA polymerase engineered from a processivity enhancing ... -
Design of a sound amplification device for mild and moderate hearing loss patients in developing countries
(Makerere University, 2021-03)From this report, readers can attain a proper understanding of the prevalence, the diagnosis and management of conductive hearing loss. A decision matrix was used to identify disabling problem of “Conductive Hearing loss”. ... -
Effect of laboratory errors on the accurate and timely reporting of bloodstream and wound infections caused by extended spectrum beta-lactamase positive escherichia.coli.
(Makerere University, 2022-01-22)Production of extended spectrum beta lactamase enzymes is one of the common mechanisms of resistance of Escherichia coli to antibiotics, thus timely detection and reporting of this phenotype is very critical and crucial ... -
Carriage of NDM carbapenemase genes among Escherichia coli isolates in human urine from Mbarara.
(Makerere University, 2021-12-20)Background: Enterobacteriaceae, a family of gram-negative bacteria to which Escherichia coli belongs easily get and transfer drug resistance genes and presence of these genes leads to production of β-lactamases. The ... -
Prevalence of extended spectrum beta lactamase resistance genes (CTX-M and TEM) among Escherichia coli isolates from Entebbe Regional Referral Hospital
(Makerere University, 2022-02)Introduction ESBL producing bacteria prevalence is on the rise and ESBL producing E.coli have been implicated in many urinary tract infections as well as septicemia. Such infections may result in prolonged hospital stays, ... -
Cytomorphological feature of thyroid gland lesions as seen in the Department of Pathology Makerere University, College of Health Sciences
(Makerere University, 2021-10)Background: Thyroid disease in East Africa continues to be endemic, despite national salt iodization. However, clinical and pathologic features predicting behaviour of thyroid cancer are still largely unknown and unstudied. ... -
Parameters for grading the toxic severity of test chemicals : a review article in the advancement of unknown drugs into the clinic
(Advances in Nanomedicine and Nanotechnology Research, 2019)Grading of toxic severity of a test chemical is a routine procedure in experimental toxicology to support regulatory policy in categorisation and harmful labeling decisions. Harmful labeling decision is usually made on the ... -
Prevalence of cervical intraepithelial neoplasia and its associated risk factors among women attending mulago national referral hospital
(Makerere University, 2021-12-10)Background: Although screening for cervical cancer is recommended for women in most countries, the incidence of cervical cancer is greater in developing countries. The Aim: The goal of this study is to determine the ... -
Design of a mechanical hands-free door opener to eliminate infection through door handles.
(Makerere University, 2020-11-27)Cross infections are defined as those that a patient acquires during his/her stay in a hospital or any other health facility, which were neither present nor incubating at the time of admission. It is absurd that many ... -
Relationship between hypermucoviscous property and antimicrobial suspectibility profile of Klebsiella pneumoniae isolates in the clinical microbiology laboratory, College of Health Sciences, Makerere University.
(Makerere University, 2022-03-22)Introduction: Hypermucoviscous K. pneumoniae which was first described in the Asian Pacific Rim in the mid-1980s and 1990 has become an emerging strain and has been considered hypervirulent. This hypermucoviscous variant ... -
Methicillin-resistant Staphylococcus aureus isolates from clinical samples received at Makerere University Clinical Microbiology Laboratory from 2017 to 2020.
(Makerere University, 2021-12)Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is highly prevalent among patients admitted to hospital wards, and is on the rise as a community associated infection. Laboratory surveillance of distribution ... -
Prevalence of fluoroquinolone resistance in salmonella species from clinical isolates at Makerere University College of Health Sciences clinical microbiology laboratory.
(Makerere University, 2021-12-01)Background. Antimicrobial resistance (AMR) is a rapidly spreading health problem across the world with the estimated annual deaths of 700,000 people due to infections by drug resistant strains of common bacterial infections. ... -
Assessing the prevalence of hypertension and prehypertension and associated risk factors among patients at the Out- Patient Department, Mulago Hospital.
(Makerere University, 2022-03)Background; Hypertension or high blood pressure is a chronic medical condition in which the blood pressure in the arteries is elevated. Hypertension has been described as the “silent killer” because initially, the disease ... -
Prevalence of benign conditions of the thyroid gland as detected by the Pathology Department among patients attending FNAC Clinic Pathology Department Makerere University College of Health Sciences
(Makerere University, 2019-07)Background: Benign thyroid disorders are common in Africa. Benign disorders are usually due to environmental toxins such as exposure to radiation, due to genetics, diet, stress, local trauma or injury, inflammation or ... -
Assessment of non lump changes among women who came with abnormal breast changes for cancer screening at FNAC Clinic at MAKCHS Pathology Department
(Makerere University, 2021-11)Background: Nipple discharge, nipple retraction and inversion the non-lump changes used. These changes could thus be helpful in early diagnosis of breast disease including breast cancer as they could be the only early ... -
Evaluation of high-level aminoglycoside resistance of enterococcal isolates in blood cultures at Makerere University clinical microbiology laboratory between 2017 to 2020
(Makerere University, 2022-03)Background: Resistance to aminoglycoside has been of great concern, since it eliminates the synergy of aminoglycosides with beta lactam antibiotics, which is the therapy of choice for most of enterococcal infection which ... -
Prevalence and antimicrobial susceptibility profile of Acinetobacter Species, among blood culture samples received at Makerere University College of Health Science (MakCHS) Clinical Microbiology Laboratory between March and August 2021.
(Makerere University, 2021-12)Acinetobacter spp. are glucose-non-fermentative, non-motile, non-fastidious, catalase-positive, oxidative-negative, aerobic gram-negative cocco-bacilli (Lin & Lan, 2014) present in the environment especially water and ... -
Prevalence and drug susceptibility pattern of pseudomonas aeruginosa using test records from February to June 2020 at Clinical Microbiology Laboratory Makerere University.
(Makerere University, 2021-12)Pseudomonas aeruginosa has become an important cause of gram negative infection especially in patients with compromised host defence mechanisms, causing infection in blood, lungs and other body parts. It is the 2nd most ... -
A project report on the design of the autobag device that performs the compression of the bag-valve-mask.
(Makerere University, 2022-02-03)The major tool used in resuscitation is the ambu bag, which requires at least two health workers to use and is tiresome to use making it less effective especially in areas with a very small patient to doctor ratio. This ...